Flumazenil Injection 0.5?mgLow price wholesale

Description Contents hide 1 Product Specifications 2 Mechanism of Action 3 Research Applications & Pharmacology 4 Safety Profile & Handling 5 Core Keywords 6 Research?Use Disclaimer Product SpecificationsSpecificationDescriptionProduct NameFlumazenil Injection (Henan Runhong)Generic NameFlumazenilCAS Number78755?81?4Molecular FormulaC??H??FN?O?Molecular Weight~303.29?g/molFormulationLyophilized sterile powder for injection, reconstitute with sterile diluentStrength0.5?mg per 5?mL vialPack Size1 vial per box (additional info by request)Approval NumberH20254517 (NMPA, China)ManufacturerHenan Runhong Pharmaceutical Co., Ltd.Storage ConditionsStore at 2–8?°C; protect from light and moistureIntended UseFor laboratory research onlyMechanism of ActionFlumazenil is a competitive antagonist at the benzodiazepine binding site of the GABA_A receptor complex, reversing sedative, hypnotic, and amnestic effects of benzodiazepine and “Z?drug” agonistsResearch Applications & PharmacologySedation reversal models: Ideal for studies on benzodiazepine overdose and anesthesia recovery .Receptor binding assays: Used to probe benzodiazepine site interactions via radiolabeled or functional displacement assays .Pharmacokinetics & metabolism: Rapid onset (1–2?min), distribution half-life ~4–11?min, terminal 40–80?min; mainly hepatic metabolism with urinary excretion (~90?95%)Withdrawal & tolerance studies: Used to precipitate acute withdrawal in long-term benzodiazepine modelsSafety Profile & HandlingPreclinical side effects: In animal models, abrupt reversal can trigger convulsions, anxiety, and withdrawal seizuresHandling: Use PPE; reconstitute under sterile conditions; visually inspect before use.Storage & disposal: Follow institutional biosafety and chemical waste protocols.Core Keywordsflumazenil injection, benzodiazepine receptor antagonist, CAS?78755?81?4, sedation reversal research, GABA_A antagonist, overdose model reagent, Henan Runhong flumazenilResearch?Use DisclaimerThis product is intended exclusively for laboratory research purposes. It is not approved for clinical, therapeutic, diagnostic, or veterinary applications. Misuse may pose serious health risks. Users must comply with institutional safety guidelines.